Search
  • Abby Zieman
    • Feb 6, 2018
    • 1 min read

Hot off the press! Zieman, A. and Coulombe PA. The keratin 16 null phenotype is modestly impacted by

Updated: Jan 3


The lab recently reported, in Experimental Dermatology, that the severity of the palmoplantar keratoderma-like manifestations that spontaneously arise in Krt16 null mice are impacted by the genetic strain background, being less severe in the FVB relative to the C57Bl/6 strain. This is relevant because the phenotypic consequences associated with very similar missense alleles in human KRT16 vary considerably in individuals with pachyonychia congenita. Find the full story on PubMed!


16 views0 comments

Recent Posts

See All

Pierre and Carole Elected as ASCB Fellows

Congratulations to Pierre and Carole to be elected as 2021 American Society for Cell Biology (ASCB) Fellows! This honor recognizes remarkable scientists who have made significant contributions to cell

Hot off the press! New publication in PNAS

Congratulations to Raji, the Coulombe lab, and the past members of the lab for publishing their collaborative research in PNAS. You can access the whole article entitled "A role for keratin 17 during

Epithelial Homeostasis in Health and Disease

COPYRIGHT © Dr. Pierre Coulombe 2021